Which antibiotic is a fluoroquinolone included in the material?

Which antibiotic is a fluoroquinolone included in the material?

• A. Rifampicin
• B. Ofloxacin
• C. Minocycline
• D. Amoxicillin

Answer: (B)

Fluoroquinolones target bacterial DNA replication by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for maintaining and duplicating DNA. Ofloxacin is a member of this class, so it fits the description of a fluoroquinolone among the options. Rifampicin is a rifamycin that inhibits RNA synthesis by targeting RNA polymerase, not a fluoroquinolone. Minocycline is a tetracycline that blocks the 30S ribosomal subunit, disrupting protein synthesis. Amoxicillin is a beta-lactam antibiotic that inhibits cell wall synthesis. Therefore, Ofloxacin is the fluoroquinolone in the list.

Fluoroquinolones target bacterial DNA replication by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for maintaining and duplicating DNA. Ofloxacin is a member of this class, so it fits the description of a fluoroquinolone among the options. Rifampicin is a rifamycin that inhibits RNA synthesis by targeting RNA polymerase, not a fluoroquinolone. Minocycline is a tetracycline that blocks the 30S ribosomal subunit, disrupting protein synthesis. Amoxicillin is a beta-lactam antibiotic that inhibits cell wall synthesis. Therefore, Ofloxacin is the fluoroquinolone in the list.